BDBM50126626 4-{Methyl-[4-(pyridin-4-yloxy)-benzenesulfonyl]-amino}-quinoline-3-carboxylic acid hydroxyamide::CHEMBL287871::N-hydroxy-4-(N-methyl-4-(pyridin-4-yloxy)phenylsulfonamido)quinoline-3-carboxamide

SMILES CN(c1c(cnc2ccccc12)C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1

InChI Key InChIKey=RAOAFDPXSFVLJD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50126626   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126626(N-hydroxy-4-(N-methyl-4-(pyridin-4-yloxy)phenylsul...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloprotease 9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126626(N-hydroxy-4-(N-methyl-4-(pyridin-4-yloxy)phenylsul...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloprotease 13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126626(N-hydroxy-4-(N-methyl-4-(pyridin-4-yloxy)phenylsul...)
Affinity DataIC50: 124nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126626(N-hydroxy-4-(N-methyl-4-(pyridin-4-yloxy)phenylsul...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibitory activity against matrix metalloprotease 1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126626(N-hydroxy-4-(N-methyl-4-(pyridin-4-yloxy)phenylsul...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed