BDBM50126884 1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-ethanone; compound with oxalic acid::CHEMBL39603

SMILES CC(=O)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1

InChI Key InChIKey=ARBBIPRORVNXCC-UHFFFAOYSA-N

Data  1 KI  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50126884   

TargetHistamine H3 receptor(Guinea pig)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50126884(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...)
Affinity DataKd:  61.7nMAssay Description:Potency at histamine H3 receptor subtype, was tested on guinea pig right ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50126884(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...)
Affinity DataKi:  84nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50126884(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...)
Affinity DataKd:  4.57E+3nMAssay Description:Potency at histamine H1 receptor subtype, was tested on guinea pig right ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50126884(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...)
Affinity DataKd:  1.02E+4nMAssay Description:Potency at histamine H2 receptor subtype, was tested on guinea pig right atriumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50126884(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...)
Affinity DataIC50: 1.04E+4nMAssay Description:Compound was tested against histamine N-methyl-transferase in rat brain [EC 2.1.1.8](relative weak affinity on rat enzyme)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed