BDBM50127061 5-(2,5-Dihydroxy-phenylethynyl)-2-hydroxy-N-phenethyl-benzamide::CHEMBL45361

SMILES Oc1ccc(O)c(c1)C#Cc1ccc(O)c(c1)C(=O)NCCc1ccccc1

InChI Key InChIKey=PEIIMQHEYAOVCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127061   

TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127061(5-(2,5-Dihydroxy-phenylethynyl)-2-hydroxy-N-phenet...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed