BDBM50127300 5-[(3',5'-Dichloro-5-cyano-biphenyl-2-ylmethoxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-pyridine-2-carbonitrile::CHEMBL289844

SMILES Cn1cncc1C(OCc1ccc(cc1-c1cc(Cl)cc(Cl)c1)C#N)c1ccc(nc1)C#N

InChI Key InChIKey=AGXJJWJDXVZXBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127300   

LigandPNGBDBM50127300(5-[(3',5'-Dichloro-5-cyano-biphenyl-2-ylmethoxy)-(...)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127300(5-[(3',5'-Dichloro-5-cyano-biphenyl-2-ylmethoxy)-(...)
Affinity DataIC50: 960nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed