BDBM50127385 3-p-Tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL51617

SMILES COC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(C)cc1)N2

InChI Key

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50127385   

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127385(3-p-Tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic ...)
Affinity DataKi:  5.40nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporter was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127385(3-p-Tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic ...)
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127385(3-p-Tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic ...)
Affinity DataIC50: 34nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127385(3-p-Tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic ...)
Affinity DataKi:  46nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127385(3-p-Tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic ...)
Affinity DataIC50: 500nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed