BDBM50127479 CHEMBL297959::N-[2-(1-Hydroxycarbamoyl-ethyl)-1,1-dioxo-2,3,4,5-tetrahydro-1H-1lambda*6*-benzo[f][1,2,5]thiadiazepin-7-yl]-3,5-dimethyl-benzamide

SMILES C[C@@H](N1CCNc2cc(NC(=O)c3cc(C)cc(C)c3)ccc2S1(=O)=O)C(=O)NO

InChI Key InChIKey=AVYWYSFUVCHTCM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50127479   

Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50127479(N-[2-(1-Hydroxycarbamoyl-ethyl)-1,1-dioxo-2,3,4,5-...)
Affinity DataKi:  94nMAssay Description:In vitro inhibitory activity against broad spectrum matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50127479(N-[2-(1-Hydroxycarbamoyl-ethyl)-1,1-dioxo-2,3,4,5-...)
Affinity DataKi:  993nMAssay Description:In vitro inhibitory activity against broad spectrum matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50127479(N-[2-(1-Hydroxycarbamoyl-ethyl)-1,1-dioxo-2,3,4,5-...)
Affinity DataKi: >4.95E+3nMAssay Description:In vitro inhibitory activity against broad spectrum matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50127479(N-[2-(1-Hydroxycarbamoyl-ethyl)-1,1-dioxo-2,3,4,5-...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibitory activity against porcine tumor necrosis factor alpha converting enzyme (pTACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed