BDBM50128949 CHEMBL292472::N-{(S)-1-[2-(4-Methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-4-methyl-benzamide

SMILES COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2ccc(C)cc2)cc1

InChI Key InChIKey=BMDHIXFGIMLKSR-NRFANRHFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128949   

TargetCathepsin S(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128949(CHEMBL292472 | N-{(S)-1-[2-(4-Methoxy-phenylamino)...)
Affinity DataIC50:  580nMAssay Description:Inhibitory activity against recombinant human cathepsin S activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128949(CHEMBL292472 | N-{(S)-1-[2-(4-Methoxy-phenylamino)...)
Affinity DataIC50: <30nMAssay Description:Inhibitory activity against recombinant human cathepsin L activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128949(CHEMBL292472 | N-{(S)-1-[2-(4-Methoxy-phenylamino)...)
Affinity DataIC50:  44nMAssay Description:Inhibitory activity against recombinant human cathepsin K activity using fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed