BDBM50128950 1H-Indole-2-carboxylic acid {(S)-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-amide::CHEMBL304918

SMILES COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2cc3ccccc3[nH]2)cc1

InChI Key InChIKey=SRYPGDMXSHZMAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128950   

TargetCathepsin K(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128950(1H-Indole-2-carboxylic acid {(S)-1-[2-(4-methoxy-p...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against recombinant human cathepsin K activity using fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128950(1H-Indole-2-carboxylic acid {(S)-1-[2-(4-methoxy-p...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against recombinant human cathepsin L activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128950(1H-Indole-2-carboxylic acid {(S)-1-[2-(4-methoxy-p...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against recombinant human cathepsin S activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed