BDBM50128956 ((S)-3-Methyl-1-{2-[4-(tetrahydro-pyran-4-yloxy)-phenylamino]-ethylcarbamoyl}-butyl)-carbamic acid benzyl ester::CHEMBL64634

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCCNc1ccc(OC2CCOCC2)cc1

InChI Key InChIKey=LHIKIUGGPSXLJE-VWLOTQADSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128956   

TargetCathepsin S(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128956(((S)-3-Methyl-1-{2-[4-(tetrahydro-pyran-4-yloxy)-p...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin S activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128956(((S)-3-Methyl-1-{2-[4-(tetrahydro-pyran-4-yloxy)-p...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against recombinant human cathepsin K activity using fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128956(((S)-3-Methyl-1-{2-[4-(tetrahydro-pyran-4-yloxy)-p...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against recombinant human cathepsin L activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed