BDBM50128957 1H-Indole-2-carboxylic acid {(S)-1-[2-(4-cyclopentylmethoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-amide::CHEMBL61382

SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)NCCNc1ccc(OCC2CCCC2)cc1

InChI Key InChIKey=PNKXLJDDFHZRNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128957   

TargetCathepsin K(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128957(1H-Indole-2-carboxylic acid {(S)-1-[2-(4-cyclopent...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human cathepsin K activity using fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128957(1H-Indole-2-carboxylic acid {(S)-1-[2-(4-cyclopent...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin S activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128957(1H-Indole-2-carboxylic acid {(S)-1-[2-(4-cyclopent...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against recombinant human cathepsin L activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed