BDBM50129776 3-(4-Amino-butyl)-6-(3-ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4-dione; hydrochloride::CHEMBL415496::Compound 11b

SMILES CCc1cc(Nc2cc(=O)n(CCCC[NH3+])c(=O)[nH]2)ccc1C

InChI Key InChIKey=RNGSTEKQZBGHDK-UHFFFAOYSA-O

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129776   

TargetDNA polymerase III PolC-type(Bacillus subtilis (strain 168))
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50129776(3-(4-Amino-butyl)-6-(3-ethyl-4-methyl-phenylamino)...)
Affinity DataKi:  62nMAssay Description:Inhibitory concentration against Bacillus subtilis DNA polymerase IIIC using [3H]dTMP 250 pM (30 degree C for 10 min)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis (strain 168))
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50129776(3-(4-Amino-butyl)-6-(3-ethyl-4-methyl-phenylamino)...)
Affinity DataKi:  62nMAssay Description:Inhibitory activity against DNA polymerase IIIC from Bacillus subtilis was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed