BDBM50130600 19-methoxy-24-methyl-26-[1-phenyl-(E)-ethylidene]-4,24-diazaheptacyclo[12.7.3.22,13.01,13.03,11.05,10.016,21]hexacosa-3(11),5(10),6,8,16(21),17,19-heptaen-20-ol::CHEMBL107420

SMILES COc1ccc2CC3N(C)CC[C@@]4([C@@H]5\C(C[C@]34Cc3c5[nH]c4ccccc34)=C(/C)c3ccccc3)c2c1O

InChI Key InChIKey=JIODEYLJTASFJC-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50130600   

TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130600(19-methoxy-24-methyl-26-[1-phenyl-(E)-ethylidene]-...)
Affinity DataKi:  0.610nMAssay Description:Binding affinity in recombinant human Opioid receptor kappa 1 transfected into chinese hamster ovary cells by displacing [3H]U-69593 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130600(19-methoxy-24-methyl-26-[1-phenyl-(E)-ethylidene]-...)
Affinity DataKi:  13nMAssay Description:Binding affinity for human Opioid receptor mu 1 transfected into chinese hamster ovary cells by displacing [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130600(19-methoxy-24-methyl-26-[1-phenyl-(E)-ethylidene]-...)
Affinity DataKi:  23nMAssay Description:Binding affinity for human Opioid receptor delta 1 transfected into chinese hamster ovary cells by displacing [3H]CI-DPDPE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130600(19-methoxy-24-methyl-26-[1-phenyl-(E)-ethylidene]-...)
Affinity DataEC50:  82nMAssay Description:Agonistic activity towards Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130600(19-methoxy-24-methyl-26-[1-phenyl-(E)-ethylidene]-...)
Affinity DataEC50:  139nMAssay Description:Effective concentration agonistic activity towards Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130600(19-methoxy-24-methyl-26-[1-phenyl-(E)-ethylidene]-...)
Affinity DataEC50:  368nMAssay Description:Agonistic activity towards Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed