BDBM50131516 2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyacetamide::2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-acetamide::CHEMBL94715

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)NCC(=O)NO

InChI Key InChIKey=XRLMAIWPTHLVKY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50131516   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131516(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyac...)
Affinity DataIC50:  753nMAssay Description:In vitro inhibition of Matrix metalloprotein-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131516(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyac...)
Affinity DataIC50:  185nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131516(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyac...)
Affinity DataIC50:  759nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50131516(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyac...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50131516(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyac...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50131516(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyac...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed