BDBM50131520 2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylthio)butanamide::2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylsulfanyl)-butyramide::CHEMBL316928

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)NC(C(=O)NO)C(C)(C)SCc1cccnc1

InChI Key InChIKey=AYPPVQRNMZPQMU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50131520   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition of Matrix metalloprotein-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3...)
Affinity DataIC50:  129nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3...)
Affinity DataIC50:  476nMAssay Description:In vitro inhibition of Matrix metalloprotein 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3...)
Affinity DataIC50:  479nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed