BDBM50131531 2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylthio)butanamide::2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylsulfanyl)-butyramide::CHEMBL96637

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N(C)C(C(=O)NO)C(C)(C)SCc1cccnc1

InChI Key InChIKey=JBVXKMHBLNDBBV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50131531   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131531(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of Matrix metalloprotein-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131531(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  54nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50131531(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50131531(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of Matrix metalloprotein 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131531(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131531(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed