BDBM50131586 4-(4-Chloro-5-phenyl-imidazol-1-yl)-benzenesulfonamide::CHEMBL118064

SMILES NS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccccc1

InChI Key InChIKey=PFBDBTJRFNNBKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131586   

TargetProstaglandin G/H synthase 2(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131586(4-(4-Chloro-5-phenyl-imidazol-1-yl)-benzenesulfona...)
Affinity DataIC50: 9nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131586(4-(4-Chloro-5-phenyl-imidazol-1-yl)-benzenesulfona...)
Affinity DataIC50: 5.10E+3nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed