BDBM50132321 CHEMBL298738

SMILES CC(C)C[C@H](NC(=O)Cc1ccc2ccccc2c1)C(=O)N[C@@H](CC1CCCCC1)[C@H](O)Cc1ccccc1C(=O)NC(C)(C)C

InChI Key InChIKey=YDKLCNFSHIKRGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132321   

TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50132321(CHEMBL298738)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed