BDBM50132340 CHEMBL299047

SMILES CCCCN(C)C(=O)[C@H](CC1CCCCC1)NC(=O)CNC(=O)Cc1cc(F)cc(F)c1

InChI Key InChIKey=YGWTVCKBAXWHCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132340   

TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50132340(CHEMBL299047)
Affinity DataIC50: 300nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed