BDBM50132484 CHEMBL3633769

SMILES COc1cc2ncnc(Nc3ccc(Cl)cc3Cl)c2cc1OCCCCCC(=O)NO

InChI Key InChIKey=HQVSMMXKDYANJJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50132484   

TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50132484(CHEMBL3633769)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human HDAC in HeLa cell nuclear extract by fluorometric assay using Fluor de Lys substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50132484(CHEMBL3633769)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant HDAC1 by fluorometric assay using Fluor de Lys substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50132484(CHEMBL3633769)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human recombinant HDAC8 by fluorometric assay using Fluor de Lys substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50132484(CHEMBL3633769)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human recombinant HDAC2 by fluorometric assay using Fluor de Lys substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50132484(CHEMBL3633769)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometric assay using Fluor de Lys substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50132484(CHEMBL3633769)
Affinity DataIC50: 84nMAssay Description:Inhibition VEGFR2 (unknown origin) for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed