BDBM50132632 (2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL110576

SMILES C[C@H]1[C@@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1)C(=O)NO

InChI Key InChIKey=SBPPAFQZTZUQSW-HRAATJIYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132632   

LigandPNGBDBM50132632((2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-benzyloxy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132632((2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-benzyloxy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Tumor necrosis factor-alpha (TNF-alpha) release in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132632((2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-benzyloxy...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132632((2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-benzyloxy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of matrix metalloprotease-13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed