BDBM50132638 (2S,3R)-2-Methyl-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-1,3-dicarboxylic acid 3-hydroxyamide 1-isopropylamide::CHEMBL111068
SMILES CC(C)NC(=O)N1CCN([C@H]([C@@H]1C)C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1
InChI Key InChIKey=GCDCQOTVUSLXRJ-PGRDOPGGSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50132638
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Tumor necrosis factor-alpha (TNF-alpha) release in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of matrix metalloprotease-13.More data for this Ligand-Target Pair