BDBM50132651 4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-trifluoromethyl-benzyl)-piperidin-4-ol::CHEMBL109509

SMILES OC1(CCN(Cc2ccc(cc2)C(F)(F)F)CC1)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=OQNPTSUNKXNSTK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132651   

TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132651(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-trifluo...)
Affinity DataKi:  104nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132651(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-trifluo...)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK293 cells More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132651(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-trifluo...)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity against human orphanin FQ receptor expressed in recombinant HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed