BDBM50132717 CHEMBL333149::Isopropyl dodecylfluorophosphonate::isopropyl dodecylphosphonofluoridate::isopropyl dodecylphosphonofluoridoate

SMILES CCCCCCCCCCCCP(F)(=O)OC(C)C

InChI Key InChIKey=SFRALHFBKRAJPW-UHFFFAOYSA-N

Data  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50132717   

TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with mouse brain memebraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with rat brain memebraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  6.30E+3nMAssay Description:Displacement of acetylcholine from AChE in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at CB1 receptor in mouse brain membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  2nMAssay Description:Displacement of radioligand from CB1 receptor in mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]anandamide from FAAH in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed