BDBM50132952 CHEMBL325430::[8-(2,4-Dichloro-phenyl)-2-methyl-quinolin-4-yl]-bis-(2-methoxy-ethyl)-amine

SMILES COCCN(CCOC)c1cc(C)nc2c(cccc12)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=ZJOLQNGRAXKVOK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132952   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132952([8-(2,4-Dichloro-phenyl)-2-methyl-quinolin-4-yl]-b...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]o-CRF as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132952([8-(2,4-Dichloro-phenyl)-2-methyl-quinolin-4-yl]-b...)
Affinity DataIC50: 14nMAssay Description:Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed