BDBM50132996 (5-Fluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone::(5-fluoro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone::CHEMBL436381

SMILES CN1CCN(CC1)C(=O)c1cc2cc(F)ccc2[nH]1

InChI Key InChIKey=MIGREITXIMIAAD-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50132996   

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50132996((5-Fluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50132996((5-Fluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50132996((5-Fluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  15.8nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50132996((5-Fluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  1.49E+7nMAssay Description:Antagonist activity at Homo sapiens (human) histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50132996((5-Fluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  1.50E+7nMAssay Description:Antagonist activity at Homo sapiens (human) histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article