BDBM50133645 ((S)-2-Methyl-1-{(1S,3aR,6aS)-1-[1-((S)-1-phenyl-ethylaminooxalyl)-butylcarbamoyl]-hexahydro-cyclopenta[c]pyrrole-2-carbonyl}-propyl)-carbamic acid isopropyl ester::CHEMBL423501

SMILES CCCC(NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@@H](NC(=O)OC(C)C)C(C)C)C(=O)C(=O)N[C@@H](C)c1ccccc1

InChI Key InChIKey=QUWLLYOWZSKAPX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133645   

TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50133645(((S)-2-Methyl-1-{(1S,3aR,6aS)-1-[1-((S)-1-phenyl-e...)
Affinity DataKi:  1.91E+3nMAssay Description:Binding affinity towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50133645(((S)-2-Methyl-1-{(1S,3aR,6aS)-1-[1-((S)-1-phenyl-e...)
Affinity DataKi:  3.00E+3nMAssay Description:Antiviral activity against human rhinovirus-14 (HRV-14) 3C protease using enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50133645(((S)-2-Methyl-1-{(1S,3aR,6aS)-1-[1-((S)-1-phenyl-e...)
Affinity DataIC50: 1.00E+5nMAssay Description:Cytotoxic activity in rat liver Huh-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed