BDBM50133750 9-[1-[5-(4-Methylsulfanyl-phenyl)-thiophen-2-yl]-meth-(Z)-ylidene]-7-aza-tricyclo[4.3.1.0*3,7*]decane-2-carboxylic acid methyl ester::CHEMBL334027

SMILES COC(=O)C1C2CCC3CC1\C(CN23)=C\c1ccc(s1)-c1ccc(SC)cc1

InChI Key

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50133750   

TargetTransporter(Rat)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50133750(9-[1-[5-(4-Methylsulfanyl-phenyl)-thiophen-2-yl]-m...)
Affinity DataKi:  273nMAssay Description:Inhibitory constant against reuptake of [3H]NE at norepinephrine transporter of rat parietal-occipital cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50133750(9-[1-[5-(4-Methylsulfanyl-phenyl)-thiophen-2-yl]-m...)
Affinity DataKi:  273nMAssay Description:Ability to inhibit reuptake of norepinephrine ([3H]NE) at norepinephrine transporter of rat parietal/occipital regionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50133750(9-[1-[5-(4-Methylsulfanyl-phenyl)-thiophen-2-yl]-m...)
Affinity DataKi:  1.65E+3nMAssay Description:Inhibitory constant against reuptake of [3H]-DA at dopamine transporter of rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50133750(9-[1-[5-(4-Methylsulfanyl-phenyl)-thiophen-2-yl]-m...)
Affinity DataKi:  1.65E+3nMAssay Description:Ability to inhibit reuptake of dopamine ([3H]DA) at dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50133750(9-[1-[5-(4-Methylsulfanyl-phenyl)-thiophen-2-yl]-m...)
Affinity DataKi:  3.32E+3nMAssay Description:Inhibitory constant against reuptake of [3H]5-HT at serotonin transporter of rat midbrain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50133750(9-[1-[5-(4-Methylsulfanyl-phenyl)-thiophen-2-yl]-m...)
Affinity DataKi:  3.32E+3nMAssay Description:Ability to inhibit reuptake of serotonin ([3H]5-HT) at serotonin transporter of rat midbrianMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed