BDBM50133793 1-{(S)-1-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-ylmethyl]-2-hydroxy-propyl}-3-(3,4,5-trimethoxy-phenyl)-urea::CHEMBL431670

SMILES COc1cc(NC(=O)N[C@@H](CN2C3CCC2CC(Cc2ccc(Cl)cc2)C3)[C@H](C)O)cc(OC)c1OC

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133793   

TargetC-C chemokine receptor type 3(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50133793(1-{(S)-1-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 2.40nMAssay Description:Compound was tested for its ability to inhibit C-C chemokine receptor type 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50133793(1-{(S)-1-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 8.20nMAssay Description:Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed