BDBM50133796 1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-methyl-ethyl}-3-(3,4,5-trimethoxy-phenyl)-urea::CHEMBL121905

SMILES COc1cc(NC(=O)N[C@H](C)CN2C3CCC2CC(Cc2ccc(Cl)cc2)C3)cc(OC)c1OC

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133796   

TargetC-C chemokine receptor type 3(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50133796(1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 4.70nMAssay Description:Compound was tested for its ability to inhibit C-C chemokine receptor type 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50133796(1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 11nMAssay Description:Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed