BDBM50133834 4-(3-Chloro-pyridin-2-yl)-piperazine-1-carboxylic acid (4-trifluoromethoxy-phenyl)-amide::CHEMBL120803

SMILES FC(F)(F)Oc1ccc(NC(=O)N2CCN(CC2)c2ncccc2Cl)cc1

InChI Key InChIKey=NPWGOHCQCPMUOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133834   

LigandPNGBDBM50133834(4-(3-Chloro-pyridin-2-yl)-piperazine-1-carboxylic ...)
Affinity DataIC50: 93nMAssay Description:Vanilloid receptor subtype 1 antagonist activity based on its ability to block capsaicin-induced (CAP) activation of the rat VR1 channel in a HEK293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50133834(4-(3-Chloro-pyridin-2-yl)-piperazine-1-carboxylic ...)
Affinity DataIC50: 261nMAssay Description:Vanilloid receptor subtype 1 antagonist activity based on its ability to block low pH-induced activation of the rat VR1 channel in a HEK293 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed