BDBM50133961 (S)-2-{(3aS,6S,6aR)-4-[5-(Difluoro-methanesulfonyl)-benzothiazol-2-yl]-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl}-pyrrolidine-1-carboxylic acid (4-isopropyl-phenyl)-amide::CHEMBL138762

SMILES CC(C)c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3c2nc3cc(ccc3s2)S(=O)(=O)C(F)F)cc1

InChI Key InChIKey=RHEUOECXBAKPTK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133961   

TargetGenome polyprotein(Human rhinovirus B)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50133961((S)-2-{(3aS,6S,6aR)-4-[5-(Difluoro-methanesulfonyl...)
Affinity DataKi:  10nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCapsid scaffolding protein(HHV-5)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50133961((S)-2-{(3aS,6S,6aR)-4-[5-(Difluoro-methanesulfonyl...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human cytomegalovirus protease in HCMV pNA assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed