BDBM50134030 9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyrrolodinopropionamido) acridine::CHEMBL336434::N,N'-(9-{[4-(dimethylamino)phenyl]amino}acridine-3,6-diyl)bis(3-pyrrolidin-1-ylpropanamide)
SMILES CN(C)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1
InChI Key InChIKey=RKPYSYRMIXRZJT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50134030
Affinity DataEC50: 115nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
Affinity DataEC50: 113nMAssay Description:Effective concentration against telomerase by TRAPMore data for this Ligand-Target Pair
Affinity DataEC50: 113nMAssay Description:Inhibition of telomerase activity from human A2780 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 6.30E+3nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP-LIG assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human telomerase assessed as unincorporated [alpha32P]dGTPMore data for this Ligand-Target Pair
TargetProtection of telomeres protein 1(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of human 35S-labeled Pot1 binding to human telomeric DNAMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Inhibition of human telomerase by TRAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human telomerase in A549 cells by TRAP assayMore data for this Ligand-Target Pair