BDBM50134223 CHEMBL3742354

SMILES COc1cc(cc2c1nc(C)c1c(C)nc(-c3cccnc3)n21)-c1cccnc1

InChI Key InChIKey=JOJOWCOCCMULDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134223   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Institute of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134223(CHEMBL3742354)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human recombinant PDE10A1 expressed in baculovirus infected insect SF21 cells using [3H]cAMP as substrate after 30 mins by scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Human)
Institute of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134223(CHEMBL3742354)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDE1B using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed