BDBM50134357 5-(2,4-Difluoro-benzyl)-4-hydroxy-3,5-dimethyl-5H-thiophen-2-one::CHEMBL331729

SMILES CC1C(=O)SC(C)(Cc2ccc(F)cc2F)C1=O

InChI Key InChIKey=JKBFWVGNESKGRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134357   

Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Birmingham

Curated by ChEMBL
LigandPNGBDBM50134357(5-(2,4-Difluoro-benzyl)-4-hydroxy-3,5-dimethyl-5H-...)
Affinity DataIC50: 2.46E+5nMAssay Description:In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed