BDBM50134389 CHEMBL3747338

SMILES Cc1cnn2c(Nc3cc(Cl)cc(Cl)c3)c(cnc12)C(N)=O

InChI Key InChIKey=BVMACYSLWMRCNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134389   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134389(CHEMBL3747338)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134389(CHEMBL3747338)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed