BDBM50134965 CHEMBL2376667
SMILES NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1cccc(CS(N)(=O)=O)c1
InChI Key InChIKey=SAWIAPXBORSMPV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50134965
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of MEK1 (unknown origin) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair