BDBM50135602 CHEMBL420259::N*1*-{2-[2-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-1-methylcarbamoyl-ethyl}-N*4*-hydroxy-2-[2-methyl-prop-(E)-ylidene]-succinamide

SMILES CNC(=O)C(Cc1c(CCN(C)C)[nH]c2ccccc12)NC(=O)C(\CC(=O)NO)=C\C(C)C

InChI Key InChIKey=ZJYOUKFITJWMLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135602   

Target72 kDa type IV collagenase(Human)
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50135602(N*1*-{2-[2-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50135602(N*1*-{2-[2-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-...)
Affinity DataIC50: 665nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed