BDBM50135822 (1-Hydroxy-1-phosphono-hexadecyl)-phosphonic acid::1-hydroxyhexadecane-1,1-diyldiphosphonic acid::CHEMBL55837::hexadecyl-1-hydroxy-1,1-bisphosphonate

SMILES CCCCCCCCCCCCCCCC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=CRTLLTFVYOUDFN-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50135822   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135822(hexadecyl-1-hydroxy-1,1-bisphosphonate | 1-hydroxy...)
Affinity DataKi:  620nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135822(hexadecyl-1-hydroxy-1,1-bisphosphonate | 1-hydroxy...)
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135822(hexadecyl-1-hydroxy-1,1-bisphosphonate | 1-hydroxy...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135822(hexadecyl-1-hydroxy-1,1-bisphosphonate | 1-hydroxy...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135822(hexadecyl-1-hydroxy-1,1-bisphosphonate | 1-hydroxy...)
Affinity DataIC50: 3.40E+5nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed