BDBM50135830 (Bis-phosphono-methyl)-cyclooctyl-ammonium::(Cyclooctylamino-phosphono-methyl)-phosphonic acid::(cyclooctylamino)methylenediphosphonic acid::CHEMBL412889::cyclooctylaminomethylen-1,1-bisphosphonate

SMILES OP(O)(O)C(=NC1CCCCCCC1)P(O)(O)=O

InChI Key InChIKey=ALNAAFRKMMHBLN-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135830   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135830(cyclooctylaminomethylen-1,1-bisphosphonate | (Cycl...)
Affinity DataKi:  230nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135830(cyclooctylaminomethylen-1,1-bisphosphonate | (Cycl...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135830(cyclooctylaminomethylen-1,1-bisphosphonate | (Cycl...)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135830(cyclooctylaminomethylen-1,1-bisphosphonate | (Cycl...)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed