BDBM50135838 (Azepan-1-yl-phosphono-methyl)-phosphonic acid::1-(Bis-phosphono-methyl)-azepanium::CHEMBL54472::[(hexahydro-1H-azepin-1yl)methylene]-1,1-bisphosphonate::azepan-1-ylmethylenediphosphonic acid

SMILES OP(O)(=O)C(N1CCCCCC1)P(O)(O)=O

InChI Key InChIKey=ZHTLUMYTKGBLAN-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50135838   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135838(azepan-1-ylmethylenediphosphonic acid | 1-(Bis-pho...)
Affinity DataKi:  49nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135838(azepan-1-ylmethylenediphosphonic acid | 1-(Bis-pho...)
Affinity DataIC50: 510nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135838(azepan-1-ylmethylenediphosphonic acid | 1-(Bis-pho...)
Affinity DataIC50: 513nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50135838(azepan-1-ylmethylenediphosphonic acid | 1-(Bis-pho...)
Affinity DataIC50: 7.44E+7nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50135838(azepan-1-ylmethylenediphosphonic acid | 1-(Bis-pho...)
Affinity DataIC50: 7.45E+7nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed