BDBM50135908 4-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-2-trifluoromethyl-benzonitrile::CHEMBL146858::Cyanonilutamide

SMILES CC1(C)NC(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=CYCKLVAQENOQPG-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135908   

TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135908(CHEMBL146858 | Cyanonilutamide | 4-(4,4-Dimethyl-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135908(CHEMBL146858 | Cyanonilutamide | 4-(4,4-Dimethyl-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135908(CHEMBL146858 | Cyanonilutamide | 4-(4,4-Dimethyl-2...)
Affinity DataKi:  1.28E+3nM IC50: 1.91E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed