BDBM50136149 3-{4-[3-(2-Fluoro-phenoxy)-3-phenyl-propyl]-piperazin-1-yl}-benzo[d]isothiazole::CHEMBL152997

SMILES Fc1ccccc1OC(CCN1CCN(CC1)c1nsc2ccccc12)c1ccccc1

InChI Key InChIKey=GLTVVRJGWNLKEM-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136149   

Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136149(3-{4-[3-(2-Fluoro-phenoxy)-3-phenyl-propyl]-pipera...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136149(3-{4-[3-(2-Fluoro-phenoxy)-3-phenyl-propyl]-pipera...)
Affinity DataKi:  70.2nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136149(3-{4-[3-(2-Fluoro-phenoxy)-3-phenyl-propyl]-pipera...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against serotonin transporter (SERT) by displacement of [3H]paroxetine in male wistar ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed