BDBM50136389 C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-[1,2,4]triazolo[4,3-a]quinazolin-7-yl]-C-(3-methyl-3H-imidazol-4-yl)-methylamine::CHEMBL140139

SMILES Cn1cncc1C(N)(c1ccc(Cl)cc1)c1ccc2c(c1)c(nc1nncn21)-c1cccc(Cl)c1

InChI Key InChIKey=SACRSUCIYWDREQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136389   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136389(C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-[1,2,4]...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed