BDBM50136413 3,4-Dichloro-N-(2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-benzamide::CHEMBL138874

SMILES Clc1ccc(cc1Cl)C(=O)NC1CCc2ccccc2NC1=O

InChI Key InChIKey=PJEBWHWSDWSNLZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136413   

TargetGlycogen phosphorylase, liver form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136413(3,4-Dichloro-N-(2-oxo-2,3,4,5-tetrahydro-1H-benzo[...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibitory concentration against recombinant human liver glycogen phosphorylase a (HLGPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136413(3,4-Dichloro-N-(2-oxo-2,3,4,5-tetrahydro-1H-benzo[...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human liver glycogen phosphorylase 1a assessed as release of phosphate from glucose-1- phosphate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, muscle form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136413(3,4-Dichloro-N-(2-oxo-2,3,4,5-tetrahydro-1H-benzo[...)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibitory concentration against recombinant human muscle glycogen phosphorylase a (HMGPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed