BDBM50136952 CHEMBL154451::N-[(4S)-4-amino-5-(pyridin-3-ylamino)pentyl]-N'-nitroguanidine

SMILES N[C@@H](CCCNC(=N)N[N+]([O-])=O)CNc1cccnc1

InChI Key InChIKey=BIAYVIUVFRKNKQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136952   

TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50136952(N-[(4S)-4-amino-5-(pyridin-3-ylamino)pentyl]-N'-ni...)
Affinity DataKi:  550nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50136952(N-[(4S)-4-amino-5-(pyridin-3-ylamino)pentyl]-N'-ni...)
Affinity DataKi:  1.41E+5nMAssay Description:Inhibitory activity against Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50136952(N-[(4S)-4-amino-5-(pyridin-3-ylamino)pentyl]-N'-ni...)
Affinity DataKi:  5.23E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed