BDBM50137547 1-[(1R,3S)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dimethyl-cyclopropyl]-2-methylsulfanyl-1H-imidazole::CHEMBL51010

SMILES CSc1nccn1[C@@H]1[C@@H](c2cccc3OCCc23)C1(C)C

InChI Key InChIKey=FFKCWNRIRDZDSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137547   

TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50137547(1-[(1R,3S)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed