BDBM50138509 1-Benzyl-3-(7-hydroxy-naphthalen-1-yl)-1-methyl-urea::CHEMBL262816

SMILES CN(Cc1ccccc1)C(=O)Nc1cccc2ccc(O)cc12

InChI Key InChIKey=HXIZBBZMZUYFQM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138509   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50138509(1-Benzyl-3-(7-hydroxy-naphthalen-1-yl)-1-methyl-ur...)
Affinity DataIC50: 1.00E+4nMAssay Description:Increased [Ca2+] influx in HEK293 cell membranes expressing human vanilloid receptor subtype 1 (inactive)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50138509(1-Benzyl-3-(7-hydroxy-naphthalen-1-yl)-1-methyl-ur...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-RTX binding to human vanilloid receptor subtype 1 expressed in HEK293 cell membranes (inactive)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed