BDBM50139012 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((1S,2R)-1-carbamoyl-2-phenyl-propylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL163334

SMILES C[C@@H]([C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1

InChI Key InChIKey=XEDWKSFZTLIHLE-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50139012   

TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139012((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  23.4nMAssay Description:Displacement of [3H]endomorphin-2 from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139012((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  26nMAssay Description:Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139012((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  28.1nMAssay Description:Displacement of [3H]dynorphin A from Opioid receptor kappa 1 of rat brain membranes (DAMGO/DADLE quenching of mu/delta receptor binding)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139012((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  69.5nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139012((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  70nMAssay Description:Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139012((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50: 89.9nMAssay Description:Inhibition of Opioid receptor mu 1 of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139012((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50: 235nMAssay Description:Inhibition of Mu opioid receptor of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139012((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of [3H]Ile5,6-deltorphin II from opioid receptor delta 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed