BDBM50139016 (R)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-1-oxo-propyl]-pyrrolidine-2-carboxylic acid [1-((S)-(S)-1-(S)-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-propyl]-amide::(S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(1R,2S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-propyl]-amide::CHEMBL355367

SMILES C[C@H]([C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)c1ccccc1

InChI Key InChIKey=GHCQVWCTWHWODK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50139016   

TargetKappa-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139016((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  990nMAssay Description:Displacement of [3H]dynorphin A from Opioid receptor kappa 1 of rat brain membranes (DAMGO/DADLE quenching of mu/delta receptor binding)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139016((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  4.91E+3nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139016((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  4.91E+3nMAssay Description:Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139016((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Ile5,6-deltorphin II from opioid receptor delta 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139016((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]endomorphin-2 from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed