BDBM50139066 CHEMBL2403494

SMILES O=C(Cc1ccccc1)Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=RHYDNPBESMLDTF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139066   

TargetElongation of very long chain fatty acids protein 1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139066(CHEMBL2403494)
Affinity DataIC50: 500nMAssay Description:Inhibition of ELOVL1 in human HEK2936E cells assessed as reduction of C26:0 LPC synthesis incubated for 48 hrs by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetElongation of very long chain fatty acids protein 1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139066(CHEMBL2403494)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ELOVL1 (unknown origin) using C22-acyl-CoA as substrate by radiometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Linyi People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50139066(CHEMBL2403494)
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of equine serum BChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Linyi People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50139066(CHEMBL2403494)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed